FASCINATION ABOUT IL-2 THERAPY FOR MELANOMA

It truly is very well comprehended that IL-2 is a pleiotropic cytokine positioned for the crossroads of T cell activation and regulation. As such, it truly is crucial to engineer an IL-2 molecule that is definitely biased to effector cells bearing the intermediate affinity receptor, like naïve and memory CD8+ T cells and NK cells, vs . Treg cells